Patient-derived glioma stem cells treated with a PLK1 (serine/threonine-protein kinase) inhibitor and stained for nuclei (blue), alpha-tubulin (green), phospho-histone H3 (red).

FISH detection of PTEN and VEGF gene loci in MCF-10.B2 cells during mammary epithelial differentiation and early mammary tumorigenesis. PTEN (red) and VEGF (green)were detected in paraformaldehyde fi...

The nucleolus during mammary epithelial differentiation and early mammary tumorigenesis. Proliferating 3D cultures of MCF-10.B2 cells treated to activate ErbB2 were stained at day 20 with ANA-N antibo...

Fluorescent image of a mouse ovary labeled with an antibody to vasa (involved in oocyte differentiation and polarity) which is localized in the oocytes within the ovary. The sample was fixed in parafo...

The relationship between the actin cytoskeleton (blue), adherens junctions (green) and phospho-Myosin Light Chain (MLC) (red) after 30 minutes of calcium stimulation.

Actin fiber organization in primary keratinocyte. There are numerous actin arcs around the periphery of the cell and actin bundles that terminate in focal adhesions (bright structures perpendicular t...

The first image in this multi-image tiff file is a stimulated emission depletion image (STED) of microtubules in a Drosophila S2 cell. The second image is the corresponding diffraction limited image ...

3T3 cells, 5min after the induction of DNA damage by microirradiation with a 405 laser. Cells were immunostained with antibody against H3K9me3 (green), a post-translational histone modification enric...

NIH 3T3 cell (mouse embryonic fibroblast line) stained for Actin (green) and DNA (blue). PLoS Biology February 2009|Volume 7|Issue 2| e1000038 Active-Site Inhibitors of mTOR Target Rapamycin-Resist...

Mouse tracheal epithelia cells (MTEC) were grown at air-liquid interface to induce differentiation, centriole amplification and ciliogenesis. Cells were fixed using ice-cold methanol for 10 min. Sampl...