Transmission electron micrograph showing the extensive accumulation of darkly stained heterochromatin at the nuclear periphery typical of many differentiated cells. Heterochromatin is excluded from re...

Transmission electron micrograph of Leydig cell nucleus from the domestic boar contains a region (arrow) thought to represent the single X chromosome which is largely heterochromatic. The chromosome i...

High resolution of a daughter micronucleus in anaphase of a dividing cell of Didinium nasutum. The chromosomes are compacted into one large heterochromatic body. Remnants of the mitotic division spind...

Transmission electron micrograph of nucleus showing the characteristic features of glutaraldehyde fixation introduced as a primary fixative in 1962 and since used routinely. Chromatin appears differen...

Phosphorylated H2AX occurs preferentially in open chromatin. Wildtype mouse embryo fibroblasts were treated with the radiomimetic drug neocarzinostatin (NCS) for 1hour prior to being fixed and immunol...

Distribution of phosphorylated H2AX occurs preferentially in open chromatin. Wildtype mouse embryo fibroblasts were treated with the histone deacetylase inhibitor trichostatinA 8 hours before being in...

Daughter micronucleus in anaphase of a dividing cell of Didinium nasutum. The chromosomes are compacted into one large heterochromatic body. Remnants of the mitotic division spindle remain inside the ...