Telomeres isolated from chicken erythrocyte nuclei following restriction endonuclease treatment, and imaged by transmission EM after uranyl acetate negative staining. Specimen was also labeled with im...

TEM image of frozen hydrated soluble chromatin isolated from chicken erythrocyte nuclei and vitrified in low salt. Polynucleosomes adopt an irregular zigzag fiber conformation (a,b,k), and show a 'ste...

TEM image of frozen hydrated soluble chromatin isolated from COS-7 cells and vitrified in 15 mM monovalent ions. The chromatin adopts an irregular zigzag fiber conformation. See Fig 2 in J Bednar et ...

Surface rendered models of chromatin organization from tomogram derived from a TEM image of epon section of a freeze-substituted mouse retina. (C) shows the region boxed in CIL:39743 where 4 regions o...

Transmission electron micrograph of the dense fibrous nuclear lamina (here labeled 'nuclear sheath')closely adpressed to the inner membrane of the nuclear envelope(arrow)in an intestinal epithelial ce...

Transmission electron micrograph showing the extensive accumulation of darkly stained heterochromatin at the nuclear periphery typical of many differentiated cells. Heterochromatin is excluded from re...

Transmission electron micrograph of Leydig cell nucleus from the domestic boar contains a region (arrow) thought to represent the single X chromosome which is largely heterochromatic. The chromosome i...

The intracellular mobility of MeCP2 (a methylated DNA-binding protein) followed in a mouse fibroblast stably expressing GFP-MeCP2 through a time series of images captured by confocal microscopy after ...

Transmission electron micrograph of nucleus showing the characteristic features of glutaraldehyde fixation introduced as a primary fixative in 1962 and since used routinely. Chromatin appears differen...

In the upper panel, transmission electron microscopy reveals a tangled mass of ~30nm diameter nuclear chromatin fibers when the contents of the nucleus from erythrocytes of the newt Notophthalmus viri...