Transmission electron micrograph of unfixed whole mounted platelet upon an EM support film from platelet rich plasma. The dense granules contain calcium rendering them electron opaque. The “dark” granules are delta granules within the platelet cytoplasm (contain calcium, adenine nucleotides, serotonin and pryrophosphates), and the bright white circles likely represent a dilated open canalicular system.
Image collected on an FEI Tecnai G2 Spirit transmission electron microscope.
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