Figure 376 from Chapter 15 (Cytoplasmic Inclusions) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. This human pancreatic acinar cell has zymogen granules crowded toward the apex. The endoplasmic reticulum cisternae that are interspersed between these secretory vesicles are more variable in width, and less highly ordered than those at the cell base. Image by Susumo Ito; Arthur Like. A PDF copy of the accompanying chapter is available on the ASCB’s BioEDUCATE website.