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Licensing
Public Domain: This image is in the public domain and thus free of any copyright restrictions. However, as is the norm in scientific publishing and as a matter of courtesy, any user should credit the content provider for any public or private use of this image whenever possible. Learn more
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*CIL – Cell Image Library accession number. Please use this to reference an image.

CIL:239*  Cite 
Description

The image depicts a live neutrophil cell showing the level of activation of the signaling protein Cdc42, a member of the Rho family of small guanosine triphosphatase (GTPase) proteins which regulates multiple cell functions, including motility, proliferation, apoptosis, and cell morphology. Here, the fluorescence level is related to protein conformational changes and interactions, with warmer colors indicating higher levels of activation.

Technical Details

See P. Nalbant et al 2004. Activation of endogenous Cdc42 visualized in living cells. Science 305:1615-1619.

Biological Sources
NCBI Organism Classification
Mus musculus
Cell Type
fibroblast
Cell Line
MEF
Cellular Component
cdc2
Attribution
Names
Klaus Hahn
Link
NIGMS Image Library
Citation
Digital Object Identifier (DOI)
doi:10.7295/W9CIL239
Archival Resource Key (ARK)
ark:/b7295/w9cil239
Grouping This image is part of a group.
Imaging
Image Type
recorded image
Image Mode
fluorescence microscopy
Parameters Imaged
fluorescence emission
Source of Contrast
differences in protein conformation
Data Qualifiers
processed data
Sample Preparation
Methods
living tissue
Relation To Intact Cell
whole mounted tissue
Dimensions
Spatial Axis Image Size Pixel Size
X 1295px ——
Y 1604px ——