CIL:228, Homo sapiens. CIL. Dataset

NCBI Organism:Homo sapiens; Cell Components:nuclear chromosome, chromosome, telomeric region; Biological process:chromosome organization, mitosis, mitotic metaphase;

Licensing

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*CIL – Cell Image Library accession number. Please use this to reference an image.

CIL:228^* Cite

Description

Image shows a metaphase spread revealing the 46 human chromosomes (blue). Telomeres have been labeled using PNA-FISH and appear as pale dots at the ends of each chromatid.

Technical Details

See E. Michishita et al. 2008. SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature 452:492-496.

Biological Sources

NCBI Organism Classification: Homo sapiens
Cellular Component: nuclear chromosome; chromosome, telomeric region

Biological Context

Biological Process: chromosome organization; mitosis; mitotic metaphase

Attribution

Names: Hesed Padilla-Nash; Thomas Ried
Link: NIGMS Image Gallery

Citation

Digital Object Identifier (DOI): doi:10.7295/W9CIL228
Archival Resource Key (ARK): ark:/b7295/w9cil228

Imaging

Image Type: charge coupled device (CCD)
Image Mode: fluorescence microscopy
Parameters Imaged: fluorescence emission
Visualization Methods: Fluorescein (FITC)
Data Qualifiers: processed data

Sample Preparation

Relation To Intact Cell: metaphase squash

Dimensions

Spatial Axis	Image Size	Pixel Size
X	900px	——
Y	958px	——