Electron micrograph of the junctional complex of intestinal epithelial cells of the rat shows the apical-most zonula occludens (tight junction), the zonula adherens (medium junction) and the macula adherens (desmosome). Image published in Faquhar and Palade, J. Cell Biol. 17: 375-412, 1963 and reprinted with permission as Figure 61 from Chapter 3 (Junctional Specializations) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. A PDF copy of the accompanying chapter is available on the ASCB's BioEDUCATE website. A PDF copy of the accompanying chapter is available on the ASCB’s BioEDUCATE website.