boi controls follicle stem cell proliferation. Germaria from wild-type in which germ cells (blue, anti-Vasa) and differentiating follicle cells (red, anti-Fas3) are labeled. Stalks between the germari...

Boi (red) localizes predominantly to apical cells in Drosophila wild-type germaria but not in germaria with UAS-boi[RNAi] expression (CIL#13742). Germ cells are identified using anti-Vasa (blue). Imag...

This light micrograph shows the outside edge of two seminiferous tubules of a mouse testis. This section is a 1um thick transverse section, stained with toluidine blue to highlight the cells, with the...

boi controls follicle stem cell proliferation. Germaria from boi[e] mutant in which germ cells (blue, anti-Vasa) and differentiating follicle cells (red, anti-Fas3) are labeled. Stalks between the ger...

Boi (green) localizes predominantly to apical cells in Drosophila wild-type germaria but not in boi[e] mutant germaria (CIL#13740). Germ cells are identified using anti-Vasa (blue). Image is Fig 2B in...

Boi (green) no longer localizes predominantly to apical cells in Drosophila boi[e] mutant germaria (compare with CIL# 13739). Germ cells are identified using anti-Vasa (blue). Image is Fig 2C in J Cel...

Boi (red) localizes predominantly to apical cells in Drosophila wild-type germaria (CIL# 13741) but not in germaria with UAS-boi[RNAi] expression in apical cells (cells expressing UAS-boi[RNAi] also e...

Patched (Ptc, green) is expressed in most cells of the Drosophila wild-type germarium including follicle stem cells. Hedgehog (Hh, red) accumulates on the surface of the apical cells. Germ cells are i...

Smoothened (Smo; green), a downstream effector of Hedgehog (Hh), is expressed in most cells of the wild-type Drosophila germarium including follicle stem cells, but is excluded from Boi- and Hh-expres...

In the absence of boi (boi[e] mutant), Hedgehog (Hh, red) is redistributed from apical cells to the extracellular space of the local follicle stem cell niche (CIL# 13744, 13745). Expression of Boi in ...