Shown is a fibroblast from a Hutchinson-Gilford Progeria syndrome patient which carries a truncation in the gene for lamin A (red, left image), a major component of the nuclear lamina. The distributio...

Distribution of Nup133, Nup43 and Nup62 (green) and tubulin (blue) in spindles assembled in vitro from Xenopus oocyte extracts. Chromosomes are stained with DAPI (blue). See Orjalo et al 2006. Mol Bio...

High Voltage transmission electron micrograph of human female (HeLa) mitotic chromosomes from metaphase arrested cell swollen in hypotonic medium and recorded at 1 MeV. This image was taken with a sp...

High Voltage (1MeV) TEM image of a squash preparation of polytene chromosomes from salivary gland of 3rd instar larva of Drosophila melanogaster showing the band-interband organization. This image wa...

Shown is a fibroblast from a Hutchinson-Gilford Progeria syndrome patient which carries a mutation in the gene for lamin A (left image, red), a major component of the nuclear lamina. Also shown is th...

Whole human female metaphase chromosome from metaphase arrested cell swollen in hypotonic medium and treated to remove histones. The resulting residual chromosome 'scaffold' was imaged at 1 MeV. This...

Whole human female metaphase chromosome from metaphase arrested cell swollen in hypotonic medium and treated to remove histones. The resulting residual chromosome 'scaffold' was imaged at 1 MeV. This...

Whole human female metaphase chromosome from metaphase arrested cell swollen in hypotonic medium and treated to remove histones. The resulting residual chromosome 'scaffold' was imaged at 1 MeV. This...

High Voltage (1MeV) TEM image of a squash preparation of polytene chromosomes from salivary gland of 3rd instar larva of Drosophila melanogaster showing the band-interband organization. This image wa...

High Voltage (1MeV) TEM image of a squash preparation of polytene chromosomes from salivary gland of 3rd instar larva of Drosophila melanogaster showing the band-interband organization. This image wa...