Transmission electron micrograph illustrating the accumulation of dense heterochromation that accompanies terminal differentiation in may cells. Shown here is a section through a polychromatophilic er...

Stages of coated pit vesicle invagination during micropinocytosis. Each frame is a portion of the surface of polychromatophilic erythroblasts from guinea pig bone marrow and various stages of vesicle...

Electron microscope autoradiograph showing labeled material in a pancreatic duct 4 hours post injection. Image corresponds to Figure 12 in Caro, L. G., and G. E. Palade. 1964 J. Cell Biol. 20:473-...

Transmission electron micrographs showing the unusual configuration of nucleoli in Sertoli cells, with smaller, highly dense spherical bodies flanking a large central body. Upper micrograph from guin...

Freeze-fracture preparation of the plasma membrane from an unspecialized area composed of Sertoli cells of the guinea pig testis. With the freeze-fracture technique, tissue is rapidly frozen and crac...

The remarkable soccer ball-like structure of coated vesicles is revealed through negative staining, and the inset panel shows a candidate model of the lattice structure. Coating of vesicles is import...

Transmission electron micrograph of a mitochondria and a lipid droplet from a guinea pig pancreas. The use of osmium tetroxide as a fixative for electron microscopy was first described by Dr. Palade a...

Transmission electron micrograph of mitochondria and mitochondrial granules from guinea pig pancreas. The use of osmium tetroxide as a fixative for electron microscopy was first described by Dr. Palad...

Nuclear pores are clearly seen in these transmission electron micrographs of cells after cryo-fixation, freeze-fracture and surface replication. Upper panel shows the outer surface of of the nuclear e...

Electron microscope autoradiograph showing the high concentration of radioactivity over the condensing vacuoles of the Golgi complex twenty minutes after injection. Image corresponds to Figure 7 in ...