Expression of R98F PINK1-YFP (green) induces mitochondrial translocation of mCherry-Parkin (red) in the presence of the mitochondrial depolarizing agent CCCP (carbonyl cyanide-m-chlorophenyl hydrazone...

YFP-Parkin (green) does not translocate to mitochondria (red) when HeLa cells are transfected with PARL (presenilin-associated rhomboid-like protein) siRNA. HeLa cells stably expressing YFP-Parkin wer...

YFP-Parkin (green) localizes to mitochondria (red) when HeLa cells are treated with the mitochondrial depolarizing agent CCCP (carbonyl cyanide-m-chlorophenyl hydrazone). HeLa cells stably expressing ...

Expression of WT PINK1-YFP (green) does not induce mitochondrial translocation of mCherry-Parkin (red) in PINK1 knock-out mouse embryonic fibroblasts (PINK1 KO MEFs). Transfected PINK1 KO MEFs were tr...

Upon mitochondrial uncoupling, wild-type PINK1-YFP (green) and mCherry-Parkin (red) are localized to mitochondria in PINK1 knock-out mouse embryonic fibroblasts (PINK1 KO MEFs). Transfected PINK1 KO M...

Upon mitochondrial uncoupling, transmembrane domain-deleted PINK1-YFP (green) fails to recruit mCherry-Parkin (red) to mitochondria in PINK1 knock-out mouse embryonic fibroblasts (PINK1 KO MEFs). Tran...

YFP-Parkin (green) localizes to mitochondria (red) when HeLa cells are transfected with control siRNA (siCtrl) and treated with the mitochondrial depolarizing agent CCCP (carbonyl cyanide-m-chlorophen...

A mutant of the vacuolar proteinase A (ngPrAdelta295-331) (green) is a substrate of ER quality control (ERQC) mechanisms, as determined by the fact that it is retained in the ER (marked by Kar2; red) ...