Nuclear pores are clearly seen in these transmission electron micrographs of cells after cryo-fixation, freeze-fracture and surface replication. Upper panel shows the outer surface of of the nuclear e...

Fluorescence images showing the distribution of GFP-ALADIN, a WD-repeat protein that is mutated in the human triple A syndrome (green), and the nucleoporin Nup358(red)within the nuclear envelope of He...

Transmission electron micrographs showing details of nuclear pores in thin sections of an erythroblast (above) and endothelial cell (below). Pores appear to be filled with dark staining material in th...

Fluorescence images showing the distribution of GFP-ALADIN, a WD-repeat protein that is mutated in the human triple A syndrome (green), and Tpr, a nucleoporin that localizes to the nucleoplasmic filam...

Transmission electron micrograph of a thin section of the nucleus of a HeLa cell expressing mutant ALADIN. Pore structure appears to be unaffected in the mutant. From a study of the role of the nuclea...

Upper panel shows a transmission electron micrograph featuring the nuclear envelope with the nuclear lamina seen here as a uniform layer between the inner nuclear membrane and more darkly staining blo...

Early transmission electron micrographs showing pore details in negatively stained preparations of nuclear envelopes. Upper panel shows the pronounced 8-fold symmetry in the closely spaced pores of t...

Grazing thin section through the nuclear envelope of a macronucleus. Nuclear pores are packed so tightly that they often form a hexagonal array with 6 pores surrounding a central pore. The pores often...

A grazing section through the edge of the nuclear envelope. This illustrates nuclear envelope pores in face view. Polysomes, chains of ribosomes, are bound to the outer membrane of the nuclear envelop...

Transmission electron micrograph of a thin section of the nucleus of a normal HeLa cell - from a study of the role of the nuclear porin ALADIN. Other images in this group show details of nuclear pore...