Transmission electron micrograph of a vacuole from a sertraline-treated drs2∆ mutant cell. This vacuole contains an undigested autophagosomes. This image is a high-magnification zoom of the cell in ...

Transmission electron micrograph of an autophago-lysosome from a sertraline-treated prototrophic wildtype cell. (40,000X). This is part of an image group highlighting multilamellar structure, CIL: 404...

Cells taken from stationary phase cultures often have larger lysosomes which contain additional paracrystalline layers. These lysosomes may be on their way to becoming the crystals which appear in lar...

Transmission electron micrograph of a yeast cell treated with 60µM sertraline. This is a high-magnification zoom of CIL 39708 showing a double-membrane autophagosome. A cresecent-shaped lipid drople...

Transmission electron micrograph of an oblong vacuole from an untreated drs2∆ mutant cell. (50,000X). This image is part of a group of yeast vacuole images (CIL:40437-40448).

Transmission electron micrograph of a representative sertraline-treated vma9 mutant cell. VMA9 encodes a subunit of the vacuolar-type H+-ATPase (V-ATPase). Sertraline treatment is associated with an ...

Transmission electron micrograph of a representative sertraline-treated chc1 mutant cell. CHC1 encodes clathrin heavy chain, which trimerizes to form triskelia that coat vesicles. The vacuolar fragmen...

A transmission electron micrograph of a representative untreated chc1 mutant cell. CHC1 encodes clathrin heavy chain, which trimerizes to form triskelia that coat vesicles. chc1 mutant cells exhibit a...

Transmission electron micrograph of a representative sertraline-treated drs2Δ mutant cell. DRS2 encodes an aminophospholipid flippase that regulates phospholipid asymmetry. A vacuole (left) contains ...

Tranmission electron micrograph of a representative untreated sac1∆ mutant cell. SAC1 encodes a phosphatase that converts phosphatidylinositol 4-phosphate (PIP) to phosphatidylinositol (PI). sac1∆...