Expression of R98F PINK1-YFP (green), consistent with localization within mitochondria, does not induce mitochondrial translocation of mCherry-Parkin (red). The R98F mutation in PINK1-YFP partially in...

The distribution of the mitochondrial inner membrane protein mitofilin, visualized here with antibody to mitofilin , highlights the very long tubular morphology of mitochondria in mouse 3T3 fibroblast...

Electron micrograph of an unmyelinated nerve Schwann cell from a rat tongue. Image made available by James D. Jamieson and the Department of Cell Biology, Yale University School of Medicine.

The distribution of the mitochondrial inner membrane protein mitofilin, visualized here with antibody to mitofilin , highlights the tubular morphology of mitochondria in mouse 3T3 fibroblasts in G1. ...

A model of the bovine mitochondrial ATP synthase at 32 Angstrom resolution as determined by electron cryomicroscopy of detergent solubilized single particles obtained from heart mitochondria. A render...

YFP-WT PINK1 (green) shows mitochondrial localization in HeLa cells following treatment with the mitochondrial depolarizing agent CCCP (carbonyl cyanide m-chlorophenyl hydrazone). When fixed cells are...

PINK1-YFP R98F (green) is localized to mitochondria in the absence of the mitochondrial depolarizing agent CCCP (carbonyl cyanide-m-chlorophenyl hydrazone). The R98F mutation in PINK1-YFP partially in...

PINK1-YFP R98F (green) is localized to mitochondria in the absence of the mitochondrial depolarizing agent CCCP (carbonyl cyanide-m-chlorophenyl hydrazone). The R98F mutation in PINK1-YFP partially in...

YFP-WT PINK1 (green) shows mitochondrial localization in HeLa cells following treatment with the mitochondrial depolarizing agent CCCP (carbonyl cyanide m-chlorophenyl hydrazone). When fixed cells are...

The F1F0 ATP synthase is a large protein complex that catalyzes the formation of ATP from ADP and inorganic phosphate using a proton gradient as a source of energy. In eukaryotes, the F1F0 ATP syntha...