Image shows a z-series of a mouse ES cell observed using 3D immuno-FISH. The ES cells carried a multi-copy insertion of an alpha-globin BAC. H3K9me3 immunostaining (red) is shown in comparison to vec...

Image shows a z-series of a mouse ES cell carrying a multi-copy alpha-globin BAC transgene array. Relative distribution of the BAC sequences, identified by DNA FISH (green) using the entire BAC as pr...

High resolution transmission electron micrograph of a portion of the macronucleus of Opercularia coarctata containing irregularly shaped heterochromatin bodies and elliptical nucleoli. Ribosome-like p...

High resolution image of the macronucleus of Coleps hirtus. Heterochromatin and nucleoli are seen as smaller and larger stained bodies, respectively, in the macronucleus. Many nuclear pores exist in t...

Transmission electron micrograph illustrating the accumulation of dense heterochromation that accompanies terminal differentiation in may cells. Shown here is a section through a polychromatophilic er...

Upper panel shows a transmission electron micrograph featuring the nuclear envelope with the nuclear lamina seen here as a uniform layer between the inner nuclear membrane and more darkly staining blo...

Image shows an immuno-FISH z-series of a mouse ES cell carrying a multi-copy insertion of alpha-globin BAC showing partial co-localization of lac operator FISH signal (green) with H3K9me3 immunostaini...

z-series image of 3D immuno-FISH of multi-copy alpha-globin BAC insertions in a mouse ES cell. Immunostaining of HP1alpha (blue) is shown versus FISH signals against total BAC sequence (red) or combi...

TEM image of epon section of a freeze-substituted mouse retina illustrating the unusual distribution of heterochromatin in rod receptor nuclei where the compact heterochromatin is centrally located. W...

Transmission electron micrograph of a pancreatic acinar cell from the bat Myotis lucifugus showing the 'classic' ultrastructural features of the nucleus after glutaraldehyde fixation. The large darkly...