Dynamics of spindle microtubules and chromosomes during cycle 11 in a transgenic Drosophila embryo expressing GFP-tubulin (green) and histone-RFP (red). Only a single confocal plane containing the cen...

Shown is a chromosome spread of a PtK1 cell pulsed with BrdU in early S phase, then treated with colcemid to arrest cells at metaphase. Spreads were immuno-labeled with FITC-conjugated anti-BrdU antib...

Spinning disk confocal time-lapse imaging of the first mitosis in a C. elegans embryo expressing GFP-histone and GFP-γ-tubulin (strain TH32). After finishing meiosis (not depicted), the female pronu...

Spinning disk confocal time-lapse imaging of mitosis in asynchronous HeLa cells transfected with control, nontargeting siRNA oligonucleotides, or siRNA oligonucleotides targeting HsKNL2. Top, nontarge...

Spinning disk confocal time-lapse imaging of the first mitosis in a C. elegans embryo that has been depleted of KNL-2 by RNAi. GFP-histone and GFP-γ-tubulin were imaged (strain TH32). Pronuclear migr...

Chromosome dynamics in a dividing LLC-PK1 cell. Images were collected with a Bessel Beam Microscope using two photon excitation. This form of microscopy provides extraordinary 4D resolution of the se...