Image shows a z-series immuno-FISH of a mouse ES cell carrying a multi-copy alpha-globin BAC insertion: HP1 gamma immunostaining (blue) is shown relative to BAC FISH signal (red) versus combined lac o...

Thin section showing nucleolus of a Human neuroblastoma SK-N-SH cell imaged with a FEI Tecnai 20 energy filtered electron microscope at 200 KV and a 20 eV energy window. Overlay of net phosphorus dist...

Thin section showing nucleolus of a Human neuroblastoma SK-N-SH cell imaged with a FEI Tecnai 20 energy filtered electron microscope at 200 KV and a 20 eV energy window. Overlay of net phosphorus dist...

Transmission electron micrograph of unstained cryo-section of a sperm cell of the starfish Patiria miniata. Echinoderm sperm nuclei are unusual in that chromatin fibers are clearly seen, allowing the...

Spinning disk confocal time-lapse imaging of the first mitosis in a C. elegans embryo expressing GFP-KNL-2 in which CeCENP-A has been depleted by RNAi in strain OD31. Diffuse nuclear GFP signal is evi...

Image shows a z-series of a mouse ES cell observed using 3D immuno-FISH. The ES cells carried a multi-copy insertion of an alpha-globin BAC. H3K9me3 immunostaining (red) is shown in comparison to vec...

Image shows a z-series of a mouse ES cell carrying a multi-copy alpha-globin BAC transgene array. Relative distribution of the BAC sequences, identified by DNA FISH (green) using the entire BAC as pr...

Image shows an immuno-FISH z-series of a mouse ES cell carrying a multi-copy insertion of alpha-globin BAC showing partial co-localization of lac operator FISH signal (green) with H3K9me3 immunostaini...

z-series image of 3D immuno-FISH of multi-copy alpha-globin BAC insertions in a mouse ES cell. Immunostaining of HP1alpha (blue) is shown versus FISH signals against total BAC sequence (red) or combi...

Phosphorylated H2AX occurs preferentially in open chromatin. Wildtype mouse embryo fibroblasts were treated with the radiomimetic drug neocarzinostatin (NCS) for 1hour prior to being fixed and immunol...