Morphology of the endoplasmic reticulum during a period of rapid cell differentiation. This micrograph shows two typical patterns of rough endoplasmic reticulum (RER) in developing liver from a one da...

Transgenic C57BL/6 mice expressing GFP-LC3 fusion protein, uninjected as control for injection with Resveratrol and/or spermidine. To avoid postmortem autophagy induction, dead mice were immediately p...

Liver of a rat exposed to chemical carcinogens. Serial sections of the liver imaged by laser scanning confocal microscopy. F-actin (red) is in bile canaliculi at junctions of the hepatocytes, which ...

This image shows the heterogeneity in the content of lysosomes near the plasma membrane between two hepatocytes and near the bile canaliculus (not visible in this field). Some of the lysosomes contai...

This section of liver from newborn rat shows glycogen deposits that are especially abundant in rat liver at this developmental stage. Deposits of glycogen, the storage form of glucose, are abundant i...

This is a view of apical domains of two adjacent hepatocytes showing the junctional complexes that attach cells to one another. The canaliculus is defined by the cell membranes of two adjacent liver c...

This is a view of apical domains of two adjacent hepatocytes in the guinea pig liver, showing the junctional complexes that attach cells to one another. The bile canaliculus (BC) is defined by the cel...

Morphology of the endoplasmic reticulum during a period of rapid cell differentiation. This micrograph shows two typical patterns of rough endoplasmic reticulum (RER) in developing liver from a one da...

This historic micrograph features the Golgi complex from a hepatocyte of a rat treated with ethanol to stimulate lipoprotein synthesis. The cisternae are distended and loaded with very low density lip...

This image shows a group of secretory vesicles loaded with very low density lipoproteins (VLDLs) located near the sinusoidal cell membrane (CM) of a hepatocyte. The fate of these VLDLs is to be secret...