Figures 442 (upper) and 443 (lower) from Chapter 16 (Cytoplasmic matrix and cytoskeleton) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. Purified preparation of actin undecorated (upper) and decorated...

To measure the in vivo mobility of the major nuclear lamina protein lamin A, human fibroblasts were transfected with the gene fused to EGFP. Fluorescence images were recorded with a confocal microsco...

Fluorescent micrograph of rat embryo fibroblast cell growing in serum stained to reveal actin stress fibres (red) and vinculin (component of focal adhesions) in green/yellow.

This photoactivation localization microscopy (PALM) image of tdEos-vinculin (red) and Dronpa-paxillin (green) illustrates that vinculin and paxillin are segregated into interlocking microdomains withi...

High voltage (1MeV) transmission electron microscopy image of an isolated metaphase chromatid pair from a mouse A9 fibroblast, showing the fiber-like structure.

NRK cells expressing a mitochondria marker, mito-RFP (red), and PSS1-CFP (green), phosphatidylserine synthase 1. A single 6 micron confocal slice was imaged on a Zeiss LSM 510 every 5.9 sec with the...

After over-night serum starvation, mouse fibroblast expressing Dyn2-GFP were stimulated with 10ng/ml PDGF. After 5min, the cells were fixed and stained with rhodamine-phalloidin. PDGF-induced dorsal m...

Human embryonic stem cell colonies. This phase contrast image shows two human embryonic stem cell colonies growing on a feeder layer of mouse embryonic fibroblasts. The stem cells actually grow in bet...

Mitochondrial distribution (visualized with Mitotracker CMXRos) was largely unaffected by partial fragmentation of the intermediate filament cytoskeleton, visualized here with vimentin antibody, after...

Association of plectin with myosin II. A gelsolin-treated REF-52 cytoskeleton immunogold labeled myosin II (10 nm). After actin depletion, intermediate filaments with plectin sidearms remain associate...