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Center for Research in Biological Systems
Basic Science Building, Room 1000
University of California, San Diego
9500 Gilman Drive
La Jolla, CA 92093-0608, USA
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Search Results for
small GTPase mediated signal transd...
(61 results)
CIL:13879
NCBI Organism Classification
Saccharomyces cerevisiae
Biological Process
cytokinesis
Cellular Component
spindle pole body
During late anaphase, Tem1 (green) localized to the spindle pole body (SPB) in cdc15-2 cells grown at the restrictive temperature. DAPI (blue) and DIC (hidden) are also shown. Compare to image CIL# 13...
CIL:13881
NCBI Organism Classification
Saccharomyces cerevisiae
Biological Process
regulation of exit from mitosis
Cellular Component
spindle pole body
Tem1-CAAX (green) is targeted away from spindle pole bodies in wild-type cells (CIL# 13880) but can also still localize to the SPB (this image). The CAAX motif from Ras2 targets proteins to the cytopl...
CIL:24044
NCBI Organism Classification
Dictyostelium discoideum AX2
Biological Process
response to electrical stimulus
Cellular Component
none specified
Starved cells of a chemotaxis-deficient mutant of Dictyostelium, KI-8 (lacking guanylyl cyclase activity) migrate toward the anode (right) with a slower migration velocity than that of wild-type cells...
CIL:13571
NCBI Organism Classification
Homo sapiens
Biological Process
Golgi organization
Cellular Component
Golgi stack
Wild-type Arf1-GFP (Arf1(WT)-GFP) (gray) colocalizes primarily at the Golgi (Giantin) (red) with Helix Pomatia Lectin (HPL) (green) in unstimulated HeLa cells. HPL binds various glycans but the Tn ant...
CIL:13572
NCBI Organism Classification
Homo sapiens
Biological Process
Golgi organization
Cellular Component
Golgi stack
Constitutively active mutant Arf1-GFP (Arf1(Q71L)-GFP) (gray) colocalizes primarily at the Golgi (Giantin) (red) with Helix Pomatia Lectin (HPL) (green) in unstimulated HeLa cells. HPL binds various g...
CIL:13575
NCBI Organism Classification
Mus musculus
Biological Process
signal transduction
Cellular Component
Golgi stack
Wild-type Arf1-GFP (Arf1(WT)-GFP) (gray) does not block redistribution of Helix Pomatia Lectin (HPL) (green) from Golgi to ER in Src-deficient SYF fibroblasts cotransfected with active Src (SrcE-DsRe...
CIL:13870
NCBI Organism Classification
Saccharomyces cerevisiae
Biological Process
cell cycle
Cellular Component
nucleus
Tem1 (green) loading onto spindle pole bodies during anaphase is severely affected in bfa1Δ cells. Compare with control image CIL# 13871. DAPI (blue) and DIC (hidden) are also shown. Image is Fig 6B,...
CIL:13873
NCBI Organism Classification
Saccharomyces cerevisiae
Biological Process
regulation of exit from mitosis
Cellular Component
cytoskeleton
Tem1 (green) constitutively targeted to spindle pole bodies in nud1-2 cells at the restrictive temperature still displayed problems positioning the spindle (this image shows an aligned spindle, CIL #1...
CIL:13878
NCBI Organism Classification
Saccharomyces cerevisiae
Biological Process
cytokinesis
Cellular Component
spindle pole body
During late anaphase, Tem1 (green) localized to the spindle pole body (SPB) in cdc15-2 bfa1Δ cells grown at the restrictive temperature. DAPI (blue) and DIC (hidden) are also shown. Compare to image ...
CIL:13882
NCBI Organism Classification
Saccharomyces cerevisiae
Biological Process
regulation of exit from mitosis
Cellular Component
nucleus
Tem1 normally localizes preferentially to the spindle pole body (SPB) that enters the daughter cell during anaphase (this image and CIL# 13885). This image shows SPB localization of eGFP-Tem1 (eGFP, g...
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