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Center for Research in Biological Systems
Basic Science Building, Room 1000
University of California, San Diego
9500 Gilman Drive
La Jolla, CA 92093-0608, USA
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Search Results for
signal transduction
(118 results)
CIL:13741
NCBI Organism Classification
Drosophila melanogaster
Biological Process
smoothened signaling pathway
Cellular Component
P granule
Boi (red) localizes predominantly to apical cells in Drosophila wild-type germaria but not in germaria with UAS-boi[RNAi] expression (CIL#13742). Germ cells are identified using anti-Vasa (blue). Imag...
CIL:26574
NCBI Organism Classification
Homo sapiens
Biological Process
protein polymerization
Cellular Component
microtubule
Immunofluorescence images used to investigate stabilization of microtubules (MTs) by Von Hippel-Lindau tumor suppressor protein (pVHL). VHL-deficient RCC-4 cells expressing wild-type VHL30 protein hav...
CIL:37338
NCBI Organism Classification
Mus musculus
Biological Process
Cellular Component
nucleus
Promyelocytic leukemia nuclear bodies (PML NBs) are dynamic nuclear organelles. They range from 0.1um to 1um in size and exist in most of mammalian cell types. The functions of PML NBs are indicated ...
CIL:24046
NCBI Organism Classification
Dictyostelium discoideum AX2
Biological Process
response to electrical stimulus
Cellular Component
cytosol
Starved Dictyostelium cells lacking both guanylyl cyclases (GCase A and GCase), but expressing GCase with an inactivated catalytic domain (sGCΔCat) and in medium supplemented with 60 µM LY294002 (a ...
CIL:31942
NCBI Organism Classification
Mus musculus
Biological Process
G-protein coupled receptor signaling pathway
Cellular Component
integral to plasma membrane
Time-lapse confocal experiment showing deltorphin II (100 nM; a selective agonist)-induced receptor internalization in primary caudate putamen neurons isolated from Oprd1-EGFP/EGFP knockin mouse. All ...
CIL:31941
NCBI Organism Classification
Mus musculus
Biological Process
G-protein coupled receptor signaling pathway
Cellular Component
integral to plasma membrane
Time-lapse confocal experiment showing SNC80 (100 nM; a selective agonist)-induced receptor internalization in primary caudate putamen neurons isolated from Oprd1-EGFP/EGFP knockin mouse. All agonists...
CIL:13458
NCBI Organism Classification
Saccharomyces cerevisiae S288c
Biological Process
retrograde vesicle-mediated transport, Golgi to ER
Cellular Component
Golgi apparatus
Intracellular localization of GFP-Vps74 in S. cerevisiae pik1-83 temperature-conditional strain grown at permissive temperature of 26C (control for 37C temperature-shift). In pik1-83 mutant after a 30...
CIL:13459
NCBI Organism Classification
Saccharomyces cerevisiae S288c
Biological Process
retrograde vesicle-mediated transport, Golgi to ER
Cellular Component
Golgi apparatus
Intracellular localization of GFP-Vps74 in S. cerevisiae pik1-83 temperature-conditional strain grown at restrictive temperature of 37C. In pik1-83 mutant after a 30 minute incubation at the restricti...
CIL:13716
NCBI Organism Classification
Homo sapiens
Biological Process
protein phosphorylation
Cellular Component
mitochondrion
Wild-type PINK1-YFP (green) is rapidly degraded in HeLa cells. HeLa cells expressing PINK1-YFP were stained with 10nM MitoTracker Red (red) for 30 min to see mitochondrial morphology and then treated ...
CIL:13724
NCBI Organism Classification
Homo sapiens
Biological Process
mitochondrion degradation
Cellular Component
mitochondrion
Expression of R98F PINK1-YFP (green) induces mitochondrial translocation of mCherry-Parkin (red) in the presence of the mitochondrial depolarizing agent CCCP (carbonyl cyanide-m-chlorophenyl hydrazone...
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