Tripolar mitosis in liver cancer cell line. Normally, dividing cells form a single metaphase plate of paired chromosomes which are pulled apart by opposing microtubule spindles. This sequence shows p...

TIRF time lapse of myosin-GFP (left), mCherry-tubulin (middle), and overlay (myosin-GFP in green and mCherry-tubulin in red) in wild-type S2 cells from metaphase to anaphase. This cell has many astral...

TIRF time lapse of myosin-GFP in a cell with a symmetric monopolar spindle from metaphase to anaphase (cell was depleted of Klp61F [kinesin-5] and BubR1 by RNAi). At anaphase, myosin-GFP concentrates ...

Shown is a mitotic PtK2 cell at metaphase immunostained for microtubules (red) and kinetochores (green) with DNA stained blue. The image was obtained using structured illumination microscopy (SIM, Del...

Surface representation of tripolar mitosis in a liver cancer cell line. Normally, dividing cells form a single metaphase plate of paired chromosomes which are pulled apart by opposing microtubule spi...

A comparison of kinesin-6 anaphase dynamics in a cell with a bipolar or monopolar spindle. (left) TIRF time lapse of kinesin-6 (Pav-GFP; green) and mCherry-tubulin (red) in a wild-type S2 cell with a ...

Time lapse of Aurora-B GFP and mCherry microtubules at the metaphase-to-anaphase transition. The laser illumination was set near to but not achieving complete total internal reflection TIRF to allow v...

Metaphase Kinetochore Dynamics: In this HeLa cell, which is expressing both a kinetochore marker (EGFP-CENP-B) and a centrosome marker (Venus-centrin), one can visualize the dynamic nature of kinetoch...