Large scale brain mosaic showing the distribution of the dopamine receptor-associated phosphoprotein DARRP-32 (green) and the vesicular monamine transporter VMAT-2 (red) in a hemisection through the a...

Time-lapse confocal experiment showing SNC80 (100 nM; a selective agonist)-induced receptor internalization in primary caudate putamen neurons isolated from Oprd1-EGFP/EGFP knockin mouse. All agonists...

Intracellular localization of GFP-Vps74 in S. cerevisiae pik1-83 temperature-conditional strain grown at permissive temperature of 26C (control for 37C temperature-shift). In pik1-83 mutant after a 30...

Intracellular localization of GFP-Vps74 in S. cerevisiae pik1-83 temperature-conditional strain grown at restrictive temperature of 37C. In pik1-83 mutant after a 30 minute incubation at the restricti...

Distribution of interneurons expressing EGFP from the 5HT3 receptor promoter (Tg(Htr3a-EGFP)DH30Gsat, www.gensat.org) in the dorsal hippocampus colabelled for the CB1 cannabinoid receptor (red) and co...

Wild-type PINK1-YFP (green) is rapidly degraded in HeLa cells. HeLa cells expressing PINK1-YFP were stained with 10nM MitoTracker Red (red) for 30 min to see mitochondrial morphology and then treated ...

Expression of R98F PINK1-YFP (green) induces mitochondrial translocation of mCherry-Parkin (red) in the presence of the mitochondrial depolarizing agent CCCP (carbonyl cyanide-m-chlorophenyl hydrazone...

Distribution of hippocampal neurons expressing EGFP from the Nr4a1/Nur77 promoter (Tg(Nr4a1-EGFP)GY139Gsat, www.gensat.org) colabelled with calbindin 28K (red, Millipore, 1:200) and stained with DAPI ...

Kre2-GFP is not efficiently maintained in the Golgi apparatus when Pik1-mediated PtdIns4P synthesis ceases, implicating Pik1 signaling in retrograde trafficking of Golgi residents. In this image, Kre2...

Expression of transmembrane domain deleted-PINK1-YFP (green) is stabilized in the mitochondira, but does not induce mitochondrial translocation of mCherry-Parkin (red) in PINK1 knock-out mouse embryon...