The time-lapse video shows live-cell imaging of an actin-GFP expressing mouse fibroblast responding to PDGF with circular dorsal ruffles. Circular dorsal ruffles are dynamic, F-actin-enriched plasma ...

Extrusion of an apoptotic cell from an HBE monolayer as shown by confocal Z-series. This set of images shows early extrusion events (middle and late events are CIL# 37909 and 37910). The bioactive lip...

Cardiac muscle, particularly from the left ventricle, is rich in mitochondria since the heart requires an efficient continuous source of energy. In this highly magnified image, showing the length of t...

Starved Dictyostelium cells lacking both guanylyl cyclases (GCase A and GCase), but expressing GCase with an inactivated catalytic domain (sGCΔCat) and in medium supplemented with 60 µM LY294002 (a ...

Extrusion of an apoptotic cell from an HBE monolayer as shown by confocal Z-series. This set of images shows middle extrusion events (early and late events are CIL# 37908 and 37910). The bioactive lip...

Localization of Alexa Fluor-594-α factor labeled endosomes (red) and Sla1-GFP labeled endocytic vesicles (green). Note that several vesicles are targeted to the prominent endosome in the (upper) moth...

The retrograde flow of microtubules oriented perpendicular to the leading edge in the lamellipodium is coupled to the movement of immediately adjacent lamellum f-actin speckles. Primary cultures of n...

The precise coupling of f-actin and parallel MT movements occurrs in all four zones of f-actin dynamic behavior: the lamellipodium,lamellum, convergence zone, and cell body. Primary cultures of newt ...

The retrograde flow of microtubules oriented perpendicular to the leading edge inthe lamellipodium is not coupled to the movement of immediately adjacent lammellipodium. Primary cultures of newt (Tar...

Apoptotic cells produce and transmit the bioactive lipid sphingosine-1-phosphate (S1P) during extrusion. This set of images shows that extrusion is blocked, as well as accumulation of S1P around the d...