HeLa cells stably expressing the BAC-encoded GFP-labeled hPrp4 snRNP and MS2-mRED protein and treated with doxycholine to express the E3 transgene. Shown is the GFP signal. Cells imaged witb a Leica ...

HeLa cells stably expressing the BAC-encoded GFP-labeled U2B snRNP and MS2-mRED protein and treated with doxycholine to express the E3 transgene. Shown is the GFP signal. Cells imaged witb a Leica SP...

Amphibian oocytes have many copies of rRNA genes that are actively transcribed. Newt oocyte nuclei were dissected, allowed to swell in a low ionic strength high pH buffer, centrifuged through a sucros...

Meiotic newt oocyte nuclei were allowed to disperse in 30 mM KCl/NaCl, centrifuged through 2% formaldehyde onto an EM grid, stained with uranyl acetate, and critical point dried. Grids were examined ...

HeLa cells stably expressing BAC-encoded GFP-labeled snRNP protein hPrp31 and imaged witb a Leica SP5 confocal microscope using a 60x 1.4NA HCX Plan Apo objective lens. The hPrp31 is confined to the ...

HeLa cells stably expressing BAC-encoded GFP-labeled snRNP protein Snu114 and imaged witb a Leica SP5 confocal microscope using a 60x 1.4NA HCX Plan Apo objective lens. The Snu114 is confined to the ...

HeLa cells stably expressing BAC-encoded GFP-labeled snRNP protein hPrp8 and treated with DRB. Cells were imaged witb a Leica SP5 confocal microscope using a 60x 1.4NA HCX Plan Apo objective lens. Fr...

Amphibian oocytes have many copies of rRNA genes that are actively transcribed. Newt ocyte nuclei were dissected, allowed to swell in a low ionic strength high pH buffer, centrifuged through a sucros...

Immunofluorescence image of HeLa cell expressing a fusion protein of GFP-polypyrimidine tract binding protein showing the localization of the perinucleolar compartment (green area) at the periphery of...

Transmission electron micrograph showing the highly compact nucleolus in the salamander hepatocyte. A finer textured central region is surrounded by a coarser region.